Yes, but if you let her get to that point, that's negligence.

It's common for ball pythons around two years old or so to start winter fasting around September/October through around March/April. That's always more frustrating for the keeper, but as long as they're healthy in the first place, it's not a problem. But she should be eating at this time of the year. Make sure your temperatures are appropriate (90 on the warm side, and mid to upper 70s ambients is what I keep my BPs at). Also make sure her hides are appropriately sized to help her feel secure and that you are not over handling her or stressing her out.

Also, here is a link to an article written by a friend of mine and an experienced ball python keeper on feeding issues: https://reptimes.com/ball-pythons-feeding/. She's also got other articles on ball python care, so feel free to browse around.