I just had a major infestation as well and finally kicked those buggers in the but HA! I'm scared of PAM and other reptile sprays, they can damage your snake or kill your snake (do a search for it). I used Natural Chemistry Reptile Relief Spray.
https://www.amazon.com/Natural-Chemi.../dp/B000NGU7NQ
What I did was pull out all the substrate. Then spray down the entire tank with reptile spray, wipe it to wet all surfaces, then let dry about 10 minutes. Then rinse it out real good with water. Then really wet a paper towel with the spray and wipe down your snake. In about 30 minutes all the mites will come crawling out of his scales and you can wipe him down a second time. I wiped a few days in a row but almost lost a snake because he looked really bad, you should only wipe them every three days at most. Probably best to wipe down once, then 30 minutes later, then wait at least a couple days at least for another wipe even if you see mites on the snake. Then put paper towels down in your tank to check for mites, I saw them daily and changed out the paper towels and wiped down the tank and let it dry every single day for 2-3 weeks or until you don't see a mite again. Be sure to keep the paper towel substrate humid. All my white snakes had red sores all over that took another couple weeks to heal after I killed all the mites.
Those mites crawl all over the room, seems like mostly on a carpet floor. So it's best to vacuum at least once a day for a couple weeks.
Don't go more than a day without changing out the substrate if you use the reptile spray, they multiply like crazy. I left my snake alone for a couple days and the mites reproduced like crazy.
I just got a new snake recently, wiped him down and a couple mites popped out. The guy I got her from was surprised.
If you switch over to paper towels be sure to spray them down with water, then take a few balled up and soaked paper towels and put them in there too to keep the humidity up. Change them all out every day until you get it under control.
Now even though my mites are gone I still have all my snakes on paper towels. Every day I have several that go to the bathroom and if I see even a single mite I go through the whole rack and change all paper towels. I still spray down all my tubs with reptile spray and let it dry. Even with a new snake with mites I only had about three days of mites and then they were totally gone again. Now that I'm mite free I clean only the tubs that are soiled by removing all the paper towels, spraying them down with reptile spray, wetting all surfaces, letting it dry, washing with water and putting down new paper towels and spraying with water. Every other day I put 3/4 cup of water in the balled up paper towels in the front of the tub for humidity.
There are many ways to fight mites but for me the reptile spray and paper towel substrate works the best and is the safest for my snakes. And it also keeps the tubs super clean, clean tubs stimulate the snakes appetite, most are eating way better than using any other substrate and spot cleaning. I find that cleaning and replacing paper towels is a lot easier and cheaper than changing out any other substrate.
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