I interact with my snakes twice a day. The first interaction is minimal, when I do the snake-room check before going to work every morning. The only reason I would handle any of them is if I need to clean the enclosure. Otherwise they get a light touch and a mist of water, and I move to the next critter.
True handling sessions are reserved for evenings when the babies aren't digesting or in shed.
I would make a point of handling a retic or boa baby more often than a ball python baby, as you want that retic or boa to be a chill, easily-handled adult.
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