I am of the belief that they are your animals, do as you see fit. However, be prepared to cull. Hopefully nothing goes wrong but...
I have stayed away from these animals so far. I really do not like the possibility of spinal problems on a snake. My long time breeding goals all revolve around supers and ALS, so these no matter how beautiful do not fit my plans. That said I am a little bit of a hypocrite because I am playing around with spider. I also deal with lessers however there are no plans for a lesser x lesser breeding.
Good luck