Honestly its your snake you can hold it as many times as you want, just look for signs of stress. The snake will let you know when she doesnt want to be held, like hissing, striking etc. IMO she rather be in her hide on her hotspot rather than being held, my snakes never leave hides unless hungry and if for some reason dont have a hide for them they hide under the paper towels. I personally handle my snakes once a week on cleaning days.