I doubt the problem will be Brian, but in how the end product turns out when it airs.
Check out the "Skunk Whisperer" and you'll see a show presented as a nice guy who has a varmit removal business. Basically he goes to people's houses and wrassles racoons and skunks and snakes at great danger to his own life, saving the poor helpless homeowners. He's got several people working for him, including one who is the typical redneck bumbling idiot, who constantly gets in over his head for laughs.
The reality is that show is completely opposite of what the man thought it would be. His business usually consists of him working with homeowners to keep wildlife out of homes, but still in their own environment. The bumbling idiot is paid by the network to do stupid stuff that will look great on camera(ahem, Chewy).
The poor star of the show was appalled and appealed to the network to change the program as that's not what he filmed, and quit allowing film crews. He's still trying to recover his image.
Anything to do with breeding animals will end up with the AR extremists coming out in force, all the snake haters pushing for making more species illegal, as well as the second BP boom in breeding which will have a ton of ill-educated folks jumping in to make a fortune.
I have great doubts that the program will be anything good. But I don't feel that way because it's Brian. Just from the history of reality TV.