If you want them gone then yeah I would use provent a mite on all my reptile enclosures. The natural chemistry can be sprayed directly onto the reptiles sparingly and avoiding the face and head. Or if you care to it can be wiped on with a clean cloth. I would toss everything in the enclosures that can't be soaked in bleach. I would trash everything made of wood. Remove all water bowls or water sources in the enclosures. All the reptiles can go in snake bags after they are sprayed. Leave the proventamite treated enclosure overnite so it can adequately air out. Don't put the reptiles back in until the following day. This will safeguard your animals and the overnite application will maximize the effects of proventamite. Repeat the procedure in 3 weeks to kill the possibility of eggs and or residual mites.