Their colors obviously dull as time goes by in between sheds, but they only shed the outer layer of skin so its not like they grow new pigment each time they have a shed. I don't think that their patterns change much as they older. That would definitely be a problem for ball python morphs. If anything their colors just aren't as vibrant as adults as they are when they are younger. My 7 month old was yellow/orange when she was younger and seems to be becoming more golden brown instead of the "high gold" look, although she still has that golden yellow color on her back, just not so much on her sides anymore.