I thought so, nothing in any research I did ever mentioned ball pythons needing anything extra. But, I'm not a nutritionist and was not 100% sure that freezing rodents didn't degrade some nutrient, so I got curious. It all started when I was browsing through the pet store and heard one of the employees trying to sell repti-cal with beta-carotene to a person that was buying a corn snake and I wanted to see what others' opinions were on supplementing snakes...the logic from the sales person was "well, people take vitamins to supplement their diets, and animals aren't that different". Luckily the woman wasn't buying his pitch