It's really difficult to tell how bad an injury is without seeing it.
If the hole is just through the skin, or even into some muscle and is not overly large, it will most likely heal up amazingly well with a little help.
Use betadine to clean it, keep her warm and clean(keep her on paper towels for cleanliness) and apply antibiotic gel WITHOUT PAIN RELIEF to the wound(try not to get it elsewhere). The vet will probably give antibiotics and will deep clean the wound.
Ball pythons can heal up from pretty extensive wounds so I would keep a positive attitude for it. If you can get a picture, that would help, but no online advice will match a good experienced reptile vet. Good luck for monday!
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