what size pythons you talking about..Get a bigger bowl or something to hold the snakes in...

after installing the batteries::

step 1 press the Tare button in the middle, this ZEROS everything out

step 2 weight the "bowl/container" your using to weigh the snakes by itself...

step 3 weight the snake in the container, get your weight number then subtract the containers weight from the "snake and container" weight.. That's just if you needed a bigger container...

Oh yeah and it has a PROGRAMMABLE Auto-Shut off