It will work as well as a glass tank.
One advantage over glass according to the warning label with my Zoo Med UTH is that glass may crack using the UTH in presence of water.
For me to keep good humidity levels I poor s few quarts of water onto my layered combo substrate every 2 weeks. Thus, I don't use an UTH in any of those setups.
One possible disadvantage, being that Acrylic is a plastic it has the potential to scratch easier than glass so be careful with cleaning and moving. Also harsh cleansers can discolor it as well.