Although I couldn't say for sure, that issue sounds similar to my red tail that I've had for almost his entire life. Whenever handling him, he swings around and twists and goes every which way. I never associated his behavior with a neurological issue, I am pretty sure he is just a grumpy snake that doesn't like being held, and perhaps feels more comfortable/more safe on the ground. Every snake is different, I would say it is more likely that she just doesn't like to be held, or doesn't feel safe, rather than having some issue. Hope this helps!