I don't think the number of holes or spacing really matters... as stated above, put 5 or 6 holes in it, about the size of a pencil on each side. Monitor your humidity. If it's too high, add some more holes. It will not likely be too low if you have a water dish in there and the right amount of heat. You should space them maybe an inch apart just so you don't have to worry about cracking the plastic, but that depends on how your making your holes, really. I have a small plastic tub my bp goes into for cage cleaning and It has 3 or 4 holes near each corner. That may be a good starting point for you.
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