I try to handle my brood at least a few days a week for at least a few minutes at a time. They just tolerate it, and don't get any benefit towards it, but it might be just enough handling to keep my track record of being bit slightly smaller!

Now when its feeding day, I never attempt to handle, especially when it gets closer to the evening and they all come out hungry...

But I handle them all, whether its a pet, or for the hobby, just so they can get used to it.