You will need to circulate air!!. Make the floor washable and the walls too. The smell of rat pee and poo is going to ruin the drywall. AC and heating that many rats produce a lot of body heat especially in the summer. We use an 80,000 btu AC unit during the summer. We also use 2 - 36" fans that vent to the outside and 2 - 24" squirrel cage fans that run 24/7 to pump fresh air into the room. Our room is 40'x24'