OWAL lists some good information about single-gene problems and genes that do not mix well. There are only a couple of genes that present fertility issues - the most problematic is the Desert gene, as females appear not to be able to lay any viable eggs. Caramels (previously called Caramel Albinos) sometimes lay high ratios of slugs to viable eggs.
When you see the "Proven Breeder" tag on an animal for sale, it is a sign to the buyer that 1) the animal is of breeding size, and 2) the animal has successfully produced viable offspring previously, which many breeder-buyers find desirable, since an unproven (virgin) animal is always a gamble - snakes gonna snake, they do not always do what we want them to do. :)
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