The general consensus seems to be not to handle until at least a meal or two... Even if she's a little nervous during the first handling after a couple weeks, she will for sure calm down more again after a few more handling sessions. It's not much of a pain at all to tame back down and doesn't take too long, because ball pythons generally are not aggressive or angry or anything to begin with. Just more shy and maybe tense.
Definitely better than handling her before she takes the two meals though, JUST in case- it would be a much bigger pain to deal with picky feeding due to stress!
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