Excuse me? Please refrain from giving advise that could injure any animal. It's detrimental to the learning of some people. And yes, a BP could harm a guinea pig. Small warm body=food. But besides that, ChicatheSnake, why would you even consider doing that? Even if they didn't harm each other, do you realize how much stress on both of them would be involved? Please don't put them together. It's not a very good idea.