Jojo usually lets me know when he wants to be handled. I have had him long enough to know that when he is out of his hide and moving about all over his enclosure that he wants to come out for a little while.
That is a very good question i have heard everything from a day to 3 days. Depending on the size of the meal. If its a small meal like a weaned rat i will wait maybe a day at least. If he eats a small rat i will wait for at least 3 days.