Sometimes a day or two after shed, I'll gently wipe down my snake with wet paper towels then dry him off. He seems to like it.
I think there are 2 types of stress.
Python regius - royal aka ball pythons - get their name from the habit of African rulers 'wearing' them around arms as jewelry. So the short-term 'stress' of being handled for a short period of time isn't going to harm them.
A much bigger concern is long-term stress due to poor husbandry and caging, because a negligent owner might not realize (or care) about the poor conditions which over time will be a serious detriment to its health.
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