Thanks guys! I plan on putting everyone in a large cooler. I only have about 15 snakes to travel with. It'll require an overnight stay which I will have them in the cooler for overnight. I might add a heat pack taped to the lid for overnight when we're at the motel. During the drive they'll be in my backseat and I'll put up sun blockers over the windows and keep it cool in the car with the AC.

The real pain is going to be the rats and mice. I really don't want a long stinky drive with them in the car. But since it's in August I don't think they'd fair well without the air conditioner.