My little girl is cranky at times about coming out of her warm, cozy hide but I don't let a little hissing stop me. Actually the last few times that I wanted to take her out she has been good and getting better at exploring. She has been shy and has a hard time leaving my arm to look around. Going back into her enclosure is the hardest part as she stretches in every direction trying to stay out. Keep working with your snake and she will get accustomed to being picked up, learning what your actions are all about. They are a great pet and so much fun to interact with.