I'm all set in the significant other department (and he loves reptiles just as much as I do!) but I've gotten no shortage of those reactions from people. I've come to kind of enjoy it rather than be put off by it. The look I got from my boyfriend's 17 year old niece when I told her we now have 13 snakes was hilarious.
Plus, the excitement when you finally find someone who IS curious about them is great. We have a friend who doesn't like pets, just never saw the point of them... But he fell in love with our snakes, and wants one from our first clutch.