Yeah ball pythons are known to be problematic. Do you feed in his tank? Or in a feeding tub? I fed my ball python in a feeding tub for probably a year and a half or two years and then he decided he wouldn't eat in it again so now I feed him in his tank. Also he decided that it needs to be dark before he'll act. It could be nothing but the usual ball python weirdness but double check your husbandry just the same.