Well its the synergistic principle that is important here. That is the combination of all three treatments is better than any one treatment alone. The betadine soaks to inhibit the germs and promote sloughing of dead tissue and scales. The silver sulfadiazine also specific to heal burned tissue. And lastly the Fortaz for the bacterial infection and sepsis that can ensue in any burn tradgedy. So doing all is better than just one or two.You cant wait for the sepsis to occur or worsen you have to treat any burn aggressively.