I breed ASF and I can provide you with some advice.

Once a colony is started, keep the colony together; don't add any new members. ASF rats are different than typical fancy/dumbo rats and have a high probability to kill outside members.

ASF are masters at escaping. Make sure you have a setup that is very secure and keep a very close eye on them in that setup for a good while to ensure they can't escape. You do not want ASF rats to escape and get loose in your home! I've actually had some chew right through some hardware cloth in the past and was lucky enough to catch a few just about to escape before it was to late.

If you are planning to feed ASF rats to your ball pythons, make sure you only feed f/t and not live!

One other tip, ASF rats take a lot longer to grow in size compared to typical rats. Make sure to plan ahead when having rodents ready for your animals if you're planning on using ASF as feeders.

Hopefully, some of that information helps out. I do have a ASF video on my YouTube channel with a breeding setup as well, feel free to check it out.