Honestly, this is just one opinion, but I had incredible success with "DE flea reptile relief" by "natural chemistry". When I got loki he had a ton on mites, I picked some reptile relief up and sprayed down the snake and let him slither around in my hands. I sprayed the same in the entire enclosure very well and let sit. I also soaked all tank decor for an hour. it's been about 2 weeks since I treated this way and have not seen one mite either on the snake, or the enclosure. I was so impressed I picked up a bottle of their flea spray for dogs as a precaution with spring coming up