I wash my hands each time before holding him, or any of my snakes, and he's otherwise very relaxed. His cage is on my desk and he'll just stay in a sedate little coil and watch or have just his head poked out of the aspen chips. He only hisses/bluffs rarely and generally I can understand why. The biting is a slow lazy thing that I almost 100% owe to him mistaking my hands for food. Other than gloves and time I'm at a loss for what to do to further acclimate this little guy.
I don't handle prey before him, we don't own any mammal pets. No rodents or anything of the sort. He's fed pinky mice alternating every 3 or 4 days with a hemostat and lately I've taken precautions not to even touch the mouse before feeding in case it transfers my scent onto the feeder.