Hybrids are the equivalent of mutts in the dog world.
Most often the hybrids are crosses of different subspecies or locales. Such as a Queensland Carpet crossed with a Irian Jaya Carpet Python. Another cross that has been seen is the Borneo Bat Eater... a Burmese Python crossed with a Reticulated Python.
The life span shouldn't be any different than that of a normal.
There in lies one of the problems.... how do you care for it? Most of the time the care requirements for the two parents will be similar so the requirements would not be too hard to figure out.
I myself prefer to stay away from the hybrids but there are some really cool ones out there.