What I did, was I would take females I wanted bred, move them and the male I wanted to use for breeding into a tub that neither of them have lived in, with clean bedding that nobody had scented yet. I left them together for about a week or so. Until the females were clearly pregnant, then the male would go back to his cage and the females would get separated into there own cages for birthing and raising. I never had any issues of the males being nasty to him once he came back in the cage. If you're worried, clean and disinfect the cage and put new bedding down then put the males all back in together. This worked very well for me. Good luck.