Thank you for the detailed response. I plan to wait at least 48 hr. Like I said she eats jumbo rats as of right now. And handling I just mean to get her out hold her or let her explore for 15 min or so nothing crazy. This is her first feeding with me so I plan to keep track of everything. Im still pretty new to all of this but ive done my research I just think there is alot of knowledgeable people here and love to hear their opnions.