As far as infertility? The desert gene seems to render females infertile (they either throw all slugs or become eggbound). I haven't heard anything about less eggs per clutch with other genes.
There are several widely accepted "lethal combo" morphs out there as well. The super woma (the "pearl") is a white snake that usually doesn't survive to hatching, and otherwise not much longer than that. Super champagnes are similar I believe. There is also much debate about the spider being a lethal super (it's recently been found to be incomplete dominant since it is allelic to blackhead but with spider blackhead x spider blackhead there are no "super spiders" produced). However, nobody has documented a significant percentage of dead eggs in spider x spider pairings, so it's an interesting gene... However, it also seems to mirror the Jaguar gene in carpet pythons (major pattern reduction linked with neurological issues) and jag x jag pairings can produce white snakes that don't survive, or more dead eggs.
Recessive breedings, the only thing I have noticed is that albino x albino pairings seem to throw higher rates of deformities than most other pairings, but I don't have statistics to back that up. Just something I've picked up on in the last few years. Perhaps it's more of an inbreeding issue than a gene issue? Who knows.
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