Hmm, it depends. All of my snakes except one have gone on a good food strike at one point (the longest being 6 months+) but after a few assist feedings, they usually go back on feed. I haven't had a problem with prey size but then again most of my animals are adults so they're on rats or occasionally a few adult mice if they get picky.
It almost always helps if you improve/change up enclosure conditions. Hatchlings feel very secure in smaller tubs (a good example is the grey ARS 10 series). Darker, humid setups are best and make sure they have a good size water bowl.
Good luck man!