Seems to me like you are doing everything you can to disturb them as little as possible. You are right about changing the soiled substrate as soon as noticed. You dont want them crawling around in their poo. (yuk)

As for her nose, could possibly be a leftover from her last shed. Keep an eye on the humidity, and hopefully it will come off with her next shed. If not, maybe a vet visit is in order.

Good luck with the babies...it sounds like you are doing everything you can to make them happy.