if it's a respiratory infection, you can get some tetracycline from a feed store (I get it from Tractor Supply Co). Put about a teaspoon (to a teaspoon and a half) in an 8oz water bottle and change it daily. That usually wipes out respiratory infections. What kind of bedding do you use? Some are more sensitive to pine bedding. I usually use pine shavings from TSC but one of my males is sensitive to it so he stays on Aspen.