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oh thats terrible 
i guess either the thermostat malfunctioned, or something was wrong with the setup. like the location of the temperature probe of the thermostat or something. thermostats need their temperature probe to get a feedback and properly regulate the temperature. it needs to be correctly placed, and if a cable breaks there.... but im speculating. it could be human error or equipment failure, no way to tell right now.
i would be more optimistic with the prognosis. really. antibiotics are a good call, you have to deal with quite a wound and dont want infections to add to the troubles. i guess the stuff on the paper towel is to help the healing process.
on the pictures, i dont think you are really looking at the actual wound, i think thats fluids from the wound, beneath the skin that would come off with the next shed. the wound will be red/white, surrounded by normal tissue. of course you would not want to remove the blister-like thing, because as long as its not leaking its still a barrier against bacteria.
depending on how big and deep the actual wound is, i would say your prognosis is far better than 50/50. the treatment plan makes a lot of sense to me. on this forum ive seen worse cases pull through. the treatment is necessary to help the wounds to heal and to prevent further damage from an infection, but royal pythons are quite resilient. i would give it a high chance of survival.
some other things: from what ive heared, in reptiles, antibiotics are most effective as injections, pills dont work that well because their digestive system is so weird.
and i would like to ask all the others what they would put on the wound (if anything) once the wound is exposed.
and its clear that the snake needs a clean bowl of fresh water at all times, but how about feeding? delay it? until when? or try to feed?
finally i hope the very best, very often BPs that have been through troubles make the best pets when you nurse them back to health. and i hope you keep us updated, no matter what happens. experiences like this can later benefit others, if they are shared, and can be used for later reference. good luck!
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