In terms of ethical behavior, to me it seems wrong if the following conditions are what you are basing your breeding on.

1. You are breeding to produce hybrids to sell.
This results in snakes that are not pure, producing all sorts of other cross overs and muddies up the general gene pool. It's easy to see people not keeping track of all the genetic details of their snakes when breeding. So when the time comes to breed them and they don't know it's a hybrid, you've got the beginnings of a gene pool pollutant.

2. If upon breeding a hybrid, it has physiological issues due to being a hybrid.
This one is a blurry line as we have the spider wobble in BPs and that is clearly a physiological issue that people don't mind and put up with. If you have done this in the past, and your hybrid had issues, public knowledge would benefit anyone possibly considering the same hybrid as they would have forewarning of possible issues. This also results in less snakes needing to be euthanized at an early age due to defects or deformities.


So far, those are the only things I can think of off the top of my head that would be problematic if you were to produce hybrids. If they can physically mate, I don't see why they wouldn't do so in the wild aside from being geographically separate.