By the way, that superheating that Randy refers to is for the outside of the rodent only. If you heat it in a baggie in a bowl of hot water as many of us do, but use water that's been boiled instead of hot tap water, you will end up with partially cooked rodent that may rupture when your snake tries to eat it. Let me assure you, it's every bit as disgusting as it sounds.

So to review, thaw and warm the rodent (either with hot water or a heat source such as a desk lamp), then grasp it with tongs or hemostats and make the mousie "dance" or "walk" in as normal a mousie way as you can manage, when snake strikes, tug back slightly on the rodent to simulate resistance, then release the mouse and let him have at it.