An S shape isn't always an indicator of a strike. Is he hissing or making any defensive strikes? My snake used to put up a front with all the posture and hissing and even a strike or two when he was younger. I use a hook and tap him a bit and then reach in and get him. Usually once he is elevated off the floor, he mellows out completely.
How old is your snake?
Gentle handling will usually make them feel secure.
Have you called his bluff yet?
Good point. If he's only making that S shape and isn't hissing or striking, it probably doesn't mean much at all. Nearly all my boas have an S shape when they turn and look at me....