RI can be a bad thing. We had a snake hold one for a year before he finally gave up. Nothing cured him. Snakes tend to hide illness real good because in the wild if a predator senses they are week then they become food. Its natural instinct. When giving injections i recommend 2 people doing it. One holding the snake and one injecting. Inject in 1st third of his body making sure you hit muscle and not his spine. Once the needle is in pull back on the plunger and if you see no blood then your in muscle. Keep the temps up in the room. Have the hot spot at 90-95 and room temp bump it to 82-86. Goodluck