I have a Lab/Newfie cross that has inflicted too many minor injuries to count. The most recent of which is a sprained toe that at first I believed to be broken.
I had hoped with this cross to get a dog with the Lab desire to please humans and the Newfie laid back attitude instead, I ended up with the Newfie stubbornness and the Lab playfulness.
Thankfully he has the Newfie gentle giant thing going on and all injuries have been due to my rough-housing with the mutt (he knows he is allowed to rough house with me but not others).