You know I wonder, because my bp just started taking large adult mice (retired breeders) a couple weeks ago. Had no problem getting them down, but it seemed like it was MUCH more work than the smaller adult mice.

I still think the best rule of thumb when pondering any feeding question, is, look at your snake's girth at its greatest point. If the rodent is less than or equal to that, then you can offer it w/o any problems.