I can't really say for sure one way or the other on this one either. Nanci does not really handle Hissy much. She doesn't seem to act much differently with either one of us. One thing I CAN say for sure, is that when I startle her in the picking up process, as soon as she flicks her tongue to smell that it is me, she calms right down. So, she certainly aquaits my scent to the "not a threat to eat me" category. Outside of that, I cannot really say.