Also, interesting side note - "High White" is an extremely misleading term, you can produce Megacolon from Irish x Irish, as SOX10 Dom is a white spotting gene and can mimic Irish markings. That said, so can Variegated (it can look Irish, Berk, etc.) But, yes, markings like that can come from several different genes. The most common (unfortunately) being SOX10 Dom.