We have huge enclosures. I could live in them ..lol
You really need a large secure enclosure. I personally do not recommend a room enclosure so to speak. If you build a naturalistic environment for your large boid, and can control heat and humidity, thats a different story. But I don't feel safe suggesting taking an already built room in your home and converting it.
Definatly need two people. For instance, on a recent trip to the vet, we had to weigh two of our large burmese pythons. to do this you first have to weigh yourself, then weigh yourself and said snake. Easier said then done, They are heavy, and awkward to hold by yourself. None the less the safety issues for yourself and the snake.
Rusty