I currently have 10 ball pythons and I handle them all at least two times a week. Really depends on their attitude on the time im cleaning their cage, changing their water, temp checking their hot spots. As the above post stated they would prefer to be in their secure hide it seems more than anything. come cleaning time or water time if one is out of its hide and crawling around and checking stuff out I will hold him/her while im changing the paper towels in the enclosure, and then sit down for a little bit with them. The one thing I notice with all 10 of my ball pythons is after handling if I put their head next to their favorite hide they almost always go in and sometimes very fast. To me that says that them being handled is more enjoyable for me than it is for them.
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