yep. actually now they are on different beddings, but that's very recent and the reactions were the same when we used the same bedding. same food too. this is a mother and son but i used to have a male who may have been related, it's uncertain and doubted, but if he had been it would have been a distant relation. That rat also didn't cause a reaction. However i have played with other female rats, my friend used the same bedding as we did, and they were from the same store but i didn't have a reaction.