Keep feeding in the enclosure and keep up regular handling. I really doubt youll have any problems. Watch your snake and learn its body language. Just because it hisses doesn't mean it will bite. I usually just make sure not to have my hand approaching them from in front of the head, I reach around and touch them mid body somewhere and then just gently scoop them out. I have several big girls that will hiss when I first touch them but they calm right down after that. And I don't handle at all on feeding day.