What are the tub conditions? Temp, humidity, hides, etc.

She's either really pissed, really scared, or really hungry.

If the tank is too hot or some other condition not right it can be making extremely stressed and irritable. Check the temps and humidity, make sure she has enough hidey hole places to feel secure.

Is she about to shed? Snakes getting to the later seconds of the shed cycle (blue eyes, etc) can get very grumpy.

You said she just ate, but what did you feed her? How big is she, how often do you feed her, and what do you feed her?